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Clinical R in Practice: The Open-Source Stack in Pharma
A 15-part series on R in pharma: pharmaverse ADaM, ARD tables, risk-based validation, targets pipelines, GxP Shiny, LLM agents — collected into a free bilingual book.
Topic
#pharmaverse
5 posts
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Building ADaM with admiral: The LEGO Method
A complete ADaM derivation built from composable bricks: the derive_* mental model, ADSL and BDS patterns, and why company templates sit on top of admiral instead of replacing it.
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Metadata-Driven Development: metacore to xportr
Spec as code: how metacore, metatools, and xportr turn your define metadata into checks, labels, and transport files — killing inconsistency at the source instead of in QC.
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The Pharmaverse Ecosystem Map: Who Builds What, and Why
admiral, tern, teal, metacore, xportr — who builds which package, how they interlock, who governs them, and how a company or a solo programmer enters the ecosystem.
SAS to R Migration in Clinical Programming: A Practical Field Guide
Why pharma is moving from SAS to R, what breaks in practice (procedures, XPT files, QC), and how to migrate a validated macro library without a rewrite.
#sas-to-r#pharmaverse#admiral#clinical-programming#xpt#validation